P-I Snake Venom Metalloproteinase Is Able to Activate the Complement System by Direct Cleavage of Central Components of the Cascade

BACKGROUND: Snake Venom Metalloproteinases (SVMPs) are amongst the key enzymes that contribute to the high toxicity of snake venom. We have recently shown that snake venoms from the Bothrops genus activate the Complement system (C) by promoting direct cleavage of C-components and generating anaphyla...

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Main Authors: Pidde-Queiroz, Giselle, Magnoli, Fábio Carlos, Portaro, Fernanda C. V., Serrano, Solange M. T., Lopes, Aline Soriano, Paes Leme, Adriana Franco, van den Berg, Carmen W., Tambourgi, Denise V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814341/
https://ncbi.nlm.nih.gov/pubmed/24205428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002519
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