P-I Snake Venom Metalloproteinase Is Able to Activate the Complement System by Direct Cleavage of Central Components of the Cascade

BACKGROUND: Snake Venom Metalloproteinases (SVMPs) are amongst the key enzymes that contribute to the high toxicity of snake venom. We have recently shown that snake venoms from the Bothrops genus activate the Complement system (C) by promoting direct cleavage of C-components and generating anaphyla...

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Hlavní autoři: Pidde-Queiroz, Giselle, Magnoli, Fábio Carlos, Portaro, Fernanda C. V., Serrano, Solange M. T., Lopes, Aline Soriano, Paes Leme, Adriana Franco, van den Berg, Carmen W., Tambourgi, Denise V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814341/
https://ncbi.nlm.nih.gov/pubmed/24205428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002519
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