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The Deacetylase Sir2 from the Yeast Clavispora lusitaniae Lacks the Evolutionarily Conserved Capacity to Generate Subtelomeric Heterochromatin

Deacetylases of the Sir2 or sirtuin family are thought to regulate life cycle progression and life span in response to nutrient availability. This family has undergone successive rounds of duplication and diversification, enabling the enzymes to perform a wide variety of biological functions. Two ev...

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Autors principals: Froyd, Cara A., Kapoor, Shivali, Dietrich, Fred, Rusche, Laura N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814328/
https://ncbi.nlm.nih.gov/pubmed/24204326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003935
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