Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

Glomerular epithelial protein 1 (GLEPP1) is a receptor tyrosine phosphatase present on the apical cell surface of the glomerular podocyte. The GLEPP1 gene (Ptpro) was disrupted at an exon coding for the NH(2)-terminal region by gene targeting in embryonic stem cells. Heterozygote mating produced the...

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Bibliografische gegevens
Hoofdauteurs: Wharram, Bryan L., Goyal, Meera, Gillespie, Patrick J., Wiggins, Jocelyn E., Kershaw, David B., Holzman, Lawrence B., Dysko, Robert C., Saunders, Thomas L., Samuelson, Linda C., Wiggins, Roger C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC381432/
https://ncbi.nlm.nih.gov/pubmed/11086029
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