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Podocyte-specific knockout of myosin 1e disrupts glomerular filtration

Myosin 1e (myo1e) is an actin-dependent molecular motor that plays an important role in kidney functions. Complete knockout of myo1e in mice and Myo1E mutations in humans are associated with nephrotic syndrome and focal segmental glomerulosclerosis. In this paper, we tested the hypothesis that myo1e...

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Detalhes bibliográficos
Main Authors: Chase, Sharon E., Encina, Christina V., Stolzenburg, Lindsay R., Tatum, Arthur H., Holzman, Lawrence B., Krendel, Mira
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469681/
https://ncbi.nlm.nih.gov/pubmed/22811491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00251.2012
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