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Biochemical fluctuations, optimisation and the linear noise approximation

BACKGROUND: Stochastic fluctuations in molecular numbers have been in many cases shown to be crucial for the understanding of biochemical systems. However, the systematic study of these fluctuations is severely hindered by the high computational demand of stochastic simulation algorithms. This is pa...

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Detalhes bibliográficos
Main Authors: Pahle, Jürgen, Challenger, Joseph D, Mendes, Pedro, McKane, Alan J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814289/
https://ncbi.nlm.nih.gov/pubmed/22805626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-86
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