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γ-AApeptides bind to RNA by mimicking RNA-binding proteins

The interactions between proteins and RNAs are of vital importance for many cellular processes, including transcription and processing of RNA, translation, and viral infections. Here we report an γ-AApeptide that can mimic HIV-1 Tat protein and bind to TAR RNAs of HIV and BIV with nanomolar affinity...

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Bibliografske podrobnosti
Main Authors: Niu, Youhong, Jones, Alisha “Jonesy”, Wu, Haifan, Varani, Gabriele, Cai, Jianfeng
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814216/
https://ncbi.nlm.nih.gov/pubmed/21826330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob05738c
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