n – 3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4(+) T-cell activation

n – 3 PUFA (polyunsaturated fatty acids), i.e. DHA (docosahexaenoic acid), found in fish oil, exhibit anti-inflammatory properties; however, the molecular mechanisms remain unclear. Since PtdIns(4,5)P(2) resides in raft domains and DHA can alter the size of rafts, we hypothesized that PtdIns(4,5)P(2...

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Detalhes bibliográficos
Main Authors: Hou, Tim Y., Monk, Jennifer M., Fan, Yang-Yi, Barhoumi, Rola, Chen, Yong Q., Rivera, Gonzalo M., McMURRAY, David N., Chapkin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814172/
https://ncbi.nlm.nih.gov/pubmed/22250985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111589
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