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The synthesis and antibacterial activity of doxycycline neoglycosides
A set of 37 doxycycline neoglycosides mediated via a C9 alkoxyamino-glycyl-based spacer reminiscent to that of tigecycline were prepared. The in vitro antibacterial assays against representative drug resistant Gram negative and Gram positive strains revealed a sugar-dependent activity profile and on...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814126/ https://ncbi.nlm.nih.gov/pubmed/23987662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np4003096 |
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