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Sensitivity of Rabbit Ventricular Action Potential and Ca(2+) Dynamics to Small Variations in Membrane Currents and Ion Diffusion Coefficients
Little is known about how small variations in ionic currents and Ca(2+) and Na(+) diffusion coefficients impact action potential and Ca(2+) dynamics in rabbit ventricular myocytes. We applied sensitivity analysis to quantify the sensitivity of Shannon et al. model (Biophys. J., 2004) to 5%–10% chang...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Publishing Corporation
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814049/ https://ncbi.nlm.nih.gov/pubmed/24222910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/565431 |
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