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Probing the Influence of a 4,6-O-Acetal on the Reactivity of Galactopyranosyl Donors: Verification of the Disarming Influence of the trans-gauche Conformation of C5–C6 Bonds

The effect of a 4,6-O-alkylidene acetal on the rate of acid-catalyzed hydrolysis of methyl galactopyranosides and of spontaneous hydrolysis of 2,4-dinitrophenyl galactopyranosides has been studied through the synthesis and hydrolysis of analogs in which O6 is replaced by a methoxymethylene unit in w...

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Main Authors: Moumé-Pymbock, Myriame, Furukawa, Takayuki, Mondal, Sujit, Crich, David
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814037/
https://ncbi.nlm.nih.gov/pubmed/23984633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja405588x
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