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Redox Modulation of eNOS by Glutaredoxin-1 through Reversible Oxidative Post-translational Modification()
S-glutathionylation is a redox-regulated modification that uncouples eNOS, switching its function from NO synthesis to •O(2)(−) generation, and serves to regulate vascular function. While in vitro or in vivo eNOS S-glutathionylation with modification of Cys689 and Cys908 of its reductase domain is t...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813969/ https://ncbi.nlm.nih.gov/pubmed/23977830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400404s |
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