EFFECT OF INTERMITTENT DOSING REGIMENS OF ERLOTINIB ON METHYLNITROSOUREA-INDUCED MAMMARY CARCINOGENESIS

EGFR inhibitors are employed in therapy of lung and pancreatic cancers, and effectively prevent cancers in multiple animal models. Although daily dosing with erlotinib is effective, weekly dosing may reduce toxicity and have advantages, particularly for prevention. We tested alternative dosing regim...

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Detalhes bibliográficos
Main Authors: Lubet, Ronald A., Szabo, Eva, Iwata, Kenneth K., Gill, Stanley C., Tucker, Chris, Bode, Ann, Steele, Vernon E., Juliana, M. Margaret, Nicastro, Holly L., Grubbs, Clinton J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813957/
https://ncbi.nlm.nih.gov/pubmed/23531447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0322
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