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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator–activated receptor γ

The CCR2-mediated recruitment of monocytes into the vessel wall plays an important role in all stages of atherosclerosis. In recent studies, we have shown that lipoproteins can modulate CCR2 expression and have identified native LDL as a positive regulator. In contrast, oxidized LDL (OxLDL), which i...

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Detalhes bibliográficos
Main Authors: Han, Ki Hoon, Chang, Mi Kyung, Boullier, Agnes, Green, Simone R., Li, Andrew, Glass, Christopher K., Quehenberger, Oswald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381395/
https://ncbi.nlm.nih.gov/pubmed/10995790
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