Genetic and Nongenetic Variation Revealed for the Principal Components of Human Gene Expression

Principal components analysis has been employed in gene expression studies to correct for population substructure and batch and environmental effects. This method typically involves the removal of variation contained in as many as 50 principal components (PCs), which can constitute a large proportio...

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Autores principales: Goldinger, Anita, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Gibson, Greg, Montgomery, Grant W., Visscher, Peter M., Powell, Joseph E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813841/
https://ncbi.nlm.nih.gov/pubmed/24026092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.153221
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