Activation, dysfunction and retention of T cells in vaccine sites after injection of incomplete Freund’s adjuvant, with or without peptide

We conducted a randomized clinical trial in 45 patients with resected AJCC stage IIB-IV melanoma to characterize cellular and molecular events at sites of immunization with incomplete Freund’s adjuvant (IFA) alone, or a melanoma vaccine in IFA. At a primary vaccine site, all patients received a mult...

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Bibliographic Details
Main Authors: Salerno, Elise P., Shea, Sofia M., Olson, Walter C., Petroni, Gina R., Smolkin, Mark E., McSkimming, Chantel, Chianese-Bullock, Kimberly A., Slingluff, Craig L.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813823/
https://ncbi.nlm.nih.gov/pubmed/23657629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1435-5
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