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The vaccine-site microenvironment induced by injection of incomplete Freund's adjuvant, with or without melanoma peptides

Cancer vaccines have not been optimized. They depend on adjuvants to create an immunogenic microenvironment for antigen presentation. However, remarkably little is understood about cellular and molecular changes induced by these adjuvants in the vaccine microenvironment. We hypothesized that vaccina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harris, Rebecca C., Chianese-Bullock, Kimberly A., Petroni, Gina R., Schaefer, Jochen T., Brill, Louis B., Molhoek, Kerrington R., Deacon, Donna H., Patterson, James W., Slingluff, Craig L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282210/
https://ncbi.nlm.nih.gov/pubmed/22130163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31823731a4
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