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The vaccine-site microenvironment induced by injection of incomplete Freund's adjuvant, with or without melanoma peptides

Cancer vaccines have not been optimized. They depend on adjuvants to create an immunogenic microenvironment for antigen presentation. However, remarkably little is understood about cellular and molecular changes induced by these adjuvants in the vaccine microenvironment. We hypothesized that vaccina...

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Detalhes bibliográficos
Main Authors: Harris, Rebecca C., Chianese-Bullock, Kimberly A., Petroni, Gina R., Schaefer, Jochen T., Brill, Louis B., Molhoek, Kerrington R., Deacon, Donna H., Patterson, James W., Slingluff, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282210/
https://ncbi.nlm.nih.gov/pubmed/22130163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31823731a4
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