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The Natural Product Magnolol as a Lead Structure for the Development of Potent Cannabinoid Receptor Agonists

Magnolol (4-allyl-2-(5-allyl-2-hydroxyphenyl)phenol), the main bioactive constituent of the medicinal plant Magnolia officinalis, and its main metabolite tetrahydromagnolol were recently found to activate cannabinoid (CB) receptors. We now investigated the structure-activity relationships of (tetrah...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fuchs, Alexander, Rempel, Viktor, Müller, Christa E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813752/
https://ncbi.nlm.nih.gov/pubmed/24204944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077739
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