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Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo

Cholangiocacinoma (CC) is a cancer disease with rising incidence. Notch signaling has been shown to be deregulated in many cancers. However, the role of this signaling pathway in the carcinogenesis of CC is still not fully explored. In this study, we investigated the effects of Notch inhibition by γ...

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מידע ביבליוגרפי
Main Authors: El Khatib, Mona, Bozko, Przemyslaw, Palagani, Vindhya, Malek, Nisar P., Wilkens, Ludwig, Plentz, Ruben R.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813685/
https://ncbi.nlm.nih.gov/pubmed/24204826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077433
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