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Promoter methylation represses AT(2)R gene and increases brain hypoxic-ischemic injury in neonatal rats
Perinatal nicotine exposure downregulated angiotensin II type 2 receptor (AT(2)R) in the developing brain and increased brain vulnerability to hypoxic-ischemic injury in male neonatal rats. We tested the hypothesis that site-specific CpG methylation at AT(2)R gene promoter contributes to the increas...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813604/ https://ncbi.nlm.nih.gov/pubmed/23978469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.08.011 |
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