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Promoter methylation represses AT(2)R gene and increases brain hypoxic-ischemic injury in neonatal rats

Perinatal nicotine exposure downregulated angiotensin II type 2 receptor (AT(2)R) in the developing brain and increased brain vulnerability to hypoxic-ischemic injury in male neonatal rats. We tested the hypothesis that site-specific CpG methylation at AT(2)R gene promoter contributes to the increas...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Yong, Xiao, Daliao, Yang, Shumei, Zhang, Lubo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813604/
https://ncbi.nlm.nih.gov/pubmed/23978469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.08.011
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