Promoter methylation represses AT(2)R gene and increases brain hypoxic-ischemic injury in neonatal rats

Perinatal nicotine exposure downregulated angiotensin II type 2 receptor (AT(2)R) in the developing brain and increased brain vulnerability to hypoxic-ischemic injury in male neonatal rats. We tested the hypothesis that site-specific CpG methylation at AT(2)R gene promoter contributes to the increas...

Full description

Saved in:
Bibliographic Details
Main Authors: Li, Yong, Xiao, Daliao, Yang, Shumei, Zhang, Lubo
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813604/
https://ncbi.nlm.nih.gov/pubmed/23978469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.08.011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items