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Endogenous IL-1 in Cognitive Function and Anxiety: A Study in IL-1RI(−/−) Mice

Interleukin-1 (IL-1) is a key pro-inflammatory cytokine, produced predominantly by peripheral immune cells but also by glia and some neuronal populations within the brain. Its signalling is mediated via the binding of IL-1α or IL-1β to the interleukin-1 type one receptor (IL-1RI). IL-1 plays a key r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murray, Carol L., Obiang, Pauline, Bannerman, David, Cunningham, Colm
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813582/
https://ncbi.nlm.nih.gov/pubmed/24205219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078385
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