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Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

BACKGROUND: Chronic neurodegeneration comprises an inflammatory response but its contribution to the progression of disease remains unclear. We have previously shown that microglial cells are primed by chronic neurodegeneration, induced by the ME7 strain of prion disease, to synthesize limited pro-i...

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Detalhes bibliográficos
Main Authors: Murray, Carol L, Skelly, Donal T, Cunningham, Colm
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119173/
https://ncbi.nlm.nih.gov/pubmed/21586125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-50
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