Inferring Polymorphism-Induced Regulatory Gene Networks Active in Human Lymphocyte Cell Lines by Weighted Linear Mixed Model Analysis of Multiple RNA-Seq Datasets

Single-nucleotide polymorphisms (SNPs) contribute to the between-individual expression variation of many genes. A regulatory (trait-associated) SNP is usually located near or within a (host) gene, possibly influencing the gene’s transcription or/and post-transcriptional modification. But its targets...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K., Zhang, Kun
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813575/
https://ncbi.nlm.nih.gov/pubmed/24205334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078868
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