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miRNA-Mediated Relationships between Cis-SNP Genotypes and Transcript Intensities in Lymphocyte Cell Lines

In metazoans, miRNAs regulate gene expression primarily through binding to target sites in the 3′ UTRs (untranslated regions) of messenger RNAs (mRNAs). Cis-acting variants within, or close to, a gene are crucial in explaining the variability of gene expression measures. Single nucleotide polymorphi...

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Autors principals: Zhang, Wensheng, Edwards, Andrea, Zhu, Dongxiao, Flemington, Erik K., Deininger, Prescott, Zhang, Kun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279374/
https://ncbi.nlm.nih.gov/pubmed/22348086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031429
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