Red-Backed Vole Brain Promotes Highly Efficient In Vitro Amplification of Abnormal Prion Protein from Macaque and Human Brains Infected with Variant Creutzfeldt-Jakob Disease Agent

Rapid antemortem tests to detect individuals with transmissible spongiform encephalopathies (TSE) would contribute to public health. We investigated a technique known as protein misfolding cyclic amplification (PMCA) to amplify abnormal prion protein (PrP(TSE)) from highly diluted variant Creutzfeld...

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Detalhes bibliográficos
Main Authors: Nemecek, Julie, Nag, Nabanita, Carlson, Christina M., Schneider, Jay R., Heisey, Dennis M., Johnson, Christopher J., Asher, David M., Gregori, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813480/
https://ncbi.nlm.nih.gov/pubmed/24205298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078710
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