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The Effect of PEG Molecular Weights on Dissolution Behavior of Simvastatin in Solid Dispersions

The purpose of the present study was to investigate the effect of polyethylene glycol (PEG) molecular weights (6000, 12000 and 20000) as solid dispersion (SD) carriers on the dissolution behavior of simvastatin. SDs with various drug : carrier ratios were prepared by solvent method and evaluated for...

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Bibliographic Details
Main Authors: Bolourchian, Noushin, Mahboobian, Mohammad Mehdi, Dadashzadeh, Simin
Format: Artigo
Language:Inglês
Published: Shaheed Beheshti University of Medical Sciences 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813355/
https://ncbi.nlm.nih.gov/pubmed/24250667
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