The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000

Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion. Methods: Spironolactone solid dispersions (1:1, 1:2 and 2:1 dru...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Akbari, Jafar, Saeedi, Majid, Morteza-Semnani, Katayoun, Kelidari, Hamid Reza, Sadegh Moghanlou, Farshad, Zareh, Gity, Rostamkalaei, Sohrab
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616884/
https://ncbi.nlm.nih.gov/pubmed/26504767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2015.059
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