Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression

Cyclin E regulates the cell cycle transition from G1 to S phase and is degraded before entry into G2 phase. Here we show that RhoBTB3, a Golgi-associated, Rho-related ATPase, regulates the S/G2 transition of the cell cycle by targeting Cyclin E for ubiquitylation. Depletion of RhoBTB3 arrested cells...

Full description

Saved in:
Bibliographic Details
Main Authors: Lu, Albert, Pfeffer, Suzanne R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812982/
https://ncbi.nlm.nih.gov/pubmed/24145166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305158
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items