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Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression
Cyclin E regulates the cell cycle transition from G1 to S phase and is degraded before entry into G2 phase. Here we show that RhoBTB3, a Golgi-associated, Rho-related ATPase, regulates the S/G2 transition of the cell cycle by targeting Cyclin E for ubiquitylation. Depletion of RhoBTB3 arrested cells...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812982/ https://ncbi.nlm.nih.gov/pubmed/24145166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305158 |
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