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Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride

We have previously shown that in renal cortex, COX-2 expression is localized to macula densa and surrounding cortical thick ascending limb of Henle (cTALH). Dietary salt restriction increases local expression of COX-2, which mediates renin production and secretion. Given that decreased luminal chlor...

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Udgivet i:J Clin Invest
Principais autores: Cheng, Hui-Fang, Wang, Jun-Ling, Zhang, Ming-Zhi, McKanna, James A., Harris, Raymond C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10974021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10318
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