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Distinguishing “Looped-Out” and “Stacked-In” DNA Bulge Conformation Using Fluorescent 2-Aminopurine Replacing a Purine Base

The conformation of a bulged DNA base, whether looped-out of the DNA helix or stacked-in between the flanking bases, can be distinguished using fluorescence spectroscopy of an inserted fluorescent base. If 2-aminopurine, a structural analog of adenine and guanine, is placed in duplex DNA as the bulg...

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Main Authors: Jiao, Yuguo, Stringfellow, Sandra, Yu, Hongtao
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812818/
https://ncbi.nlm.nih.gov/pubmed/11922846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2002.10506795
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