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Osteoclasts Lose Innate Inflammatory Reactivity to Metal and Polymer Implant Debris Compared to Monocytes/Macrophages

Long-term aseptic failures of joint replacements are generally attributed to implant debris-induced inflammation and osteolysis. This response is largely mediated by immune and bone cells (monocytes/macrophages and osteoclasts, respectively), that in the presence of implant debris (e.g. metal partic...

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Библиографические подробности
Главные авторы: Yadav, Jessica, Samelko, Lauryn, Gilvar, Phil, McAllister, Kyron, Hallab, Nadim James
Формат: Artigo
Язык:Inglês
Опубликовано: Bentham Open 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812786/
https://ncbi.nlm.nih.gov/pubmed/24198853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874325001307010605
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