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Titration of GLI3 Repressor Activity by Sonic Hedgehog Signaling Is Critical for Maintaining Multiple Adult Neural Stem Cell and Astrocyte Functions

Sonic hedgehog (SHH), a key regulator of embryonic neurogenesis, signals directly to neural stem cells (NSCs) in the subventricular zone (SVZ) and to astrocytes in the adult mouse forebrain. The specific mechanism by which the GLI2 and GLI3 transcriptional activators (GLI2(A) and GLI3(A)) and repres...

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Bibliografiset tiedot
Päätekijät: Petrova, Ralitsa, Garcia, A. Denise R., Joyner, Alexandra L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812512/
https://ncbi.nlm.nih.gov/pubmed/24174682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2042-13.2013
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