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2D IR Cross Peaks Reveal Hydrogen-Deuterium Exchange with Single Residue Specificity
A form of chemical exchange, hydrogen-deuterium exchange (HDX), has long been used as a method for studying the secondary and tertiary structure of peptides and proteins using mass spectrometry and NMR spectroscopy. Using 2D IR (two dimensional infrared) spectroscopy, we resolve cross peaks between...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812256/ https://ncbi.nlm.nih.gov/pubmed/23659731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp402942s |
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