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Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets
Some experimental evidence indicates that uncommon BRAF mutations consisting in the substitution of 2 adjacent nucleotides within codon 600 are in a cis configuration and associate with BRAF gene amplification. These findings suggest that BRAF(V600) mutations are unlikely to occur as homozygous alte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812198/ https://ncbi.nlm.nih.gov/pubmed/24179707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25594 |
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