Loss of miR-10a Activates Lpo and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice

miRNAs are small regulatory RNAs that, due to their considerable potential to target a wide range of mRNAs, are implicated in essentially all biological process, including cancer. miR-10a is particularly interesting considering its conserved location in the Hox cluster of developmental regulators. A...

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Detalhes bibliográficos
Main Authors: Stadthagen, Gustavo, Tehler, Disa, Høyland-Kroghsbo, Nina Molin, Wen, Jiayu, Krogh, Anders, Jensen, Klaus T., Santoni-Rugiu, Eric, Engelholm, Lars H., Lund, Anders H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812087/
https://ncbi.nlm.nih.gov/pubmed/24204315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003913
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