IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection

In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did not associate with parasite specific antibody responses. Re-infection of B cell-specific I...

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Autores principales: Horsnell, William G. C., Darby, Matthew G., Hoving, Jennifer C., Nieuwenhuizen, Natalie, McSorley, Henry J., Ndlovu, Hlumani, Bobat, Saeeda, Kimberg, Matti, Kirstein, Frank, Cutler, Anthony J., DeWals, Benjamin, Cunningham, Adam F., Brombacher, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812011/
https://ncbi.nlm.nih.gov/pubmed/24204255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003662
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