IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection

In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did not associate with parasite specific antibody responses. Re-infection of B cell-specific I...

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Detalhes bibliográficos
Main Authors: Horsnell, William G. C., Darby, Matthew G., Hoving, Jennifer C., Nieuwenhuizen, Natalie, McSorley, Henry J., Ndlovu, Hlumani, Bobat, Saeeda, Kimberg, Matti, Kirstein, Frank, Cutler, Anthony J., DeWals, Benjamin, Cunningham, Adam F., Brombacher, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812011/
https://ncbi.nlm.nih.gov/pubmed/24204255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003662
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