A Cross-Reactive Monoclonal Antibody to Nematode Haemoglobin Enhances Protective Immune Responses to Nippostrongylus brasiliensis

BACKGROUND: Nematode secreted haemoglobins have unusually high affinity for oxygen and possess nitric oxide deoxygenase, and catalase activity thought to be important in protection against host immune responses to infection. In this study, we generated a monoclonal antibody (48Eg) against haemoglobi...

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Hauptverfasser: Nieuwenhuizen, Natalie E., Meter, Jeanne M., Horsnell, William G., Hoving, J. Claire, Fick, Lizette, Sharp, Michael F., Darby, Matthew G., Parihar, Suraj P., Brombacher, Frank, Lopata, Andreas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757078/
https://ncbi.nlm.nih.gov/pubmed/24009787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002395
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