IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection

In this study, B cell function in protective T(H)2 immunity against N. brasiliensis infection was investigated. Protection against secondary infection depended on IL-4Rα and IL-13; but not IL-4. Protection did not associate with parasite specific antibody responses. Re-infection of B cell-specific I...

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Main Authors: Horsnell, William G. C., Darby, Matthew G., Hoving, Jennifer C., Nieuwenhuizen, Natalie, McSorley, Henry J., Ndlovu, Hlumani, Bobat, Saeeda, Kimberg, Matti, Kirstein, Frank, Cutler, Anthony J., DeWals, Benjamin, Cunningham, Adam F., Brombacher, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812011/
https://ncbi.nlm.nih.gov/pubmed/24204255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003662
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