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Deacetylase Rpd3 Facilitates Checkpoint Adaptation by Preventing Rad53 Overactivation

The DNA damage checkpoint is tightly controlled. After its activation, the checkpoint machinery is inactivated once lesions are repaired or undergoes adaptation if the DNA damage is unable to be repaired. Protein acetylation has been shown to play an important role in DNA damage checkpoint activatio...

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Detalhes bibliográficos
Main Authors: Tao, Ran, Xue, Hua, Zhang, Jianping, Liu, Jieyuan, Deng, Haiteng, Chen, Ye-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811893/
https://ncbi.nlm.nih.gov/pubmed/23979600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00618-13
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