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The Membrane-Proximal KXGFFKR Motif of α-Integrin Mediates Chemoresistance
Cell adhesion-mediated drug resistance contributes to minimal residual disease and relapse in hematological malignancies. Here, we show that adhesion of Jurkat T-acute lymphoblastic leukemia cells to substrates engaging α4β1-integrin or α5β1-integrin promotes chemoresistance to doxorubicin-induced a...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811891/ https://ncbi.nlm.nih.gov/pubmed/24001772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00580-13 |
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