Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death

Therapy-induced presentation of cell surface calreticulin (CRT) is a pro-phagocytic immunogen beneficial for invoking anti-tumor immunity. Here, we characterized the roles of ERp57 and α-integrins as CRT-interacting proteins that coordinately regulate CRT translocation from the ER to the surface dur...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Liu, Chi-Chao, Leclair, Pascal, Pedari, Foujan, Vieira, Heidi, Monajemi, Mahdis, Sly, Laura M., Reid, Gregor S., Lim, Chinten James
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546883/
https://ncbi.nlm.nih.gov/pubmed/31192123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00411
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