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Tetrahymena Telomerase Holoenzyme Assembly, Activation, and Inhibition by Domains of the p50 Central Hub

The eukaryotic reverse transcriptase, telomerase, adds tandem telomeric repeats to chromosome ends to promote genome stability. The fully assembled telomerase holoenzyme contains a ribonucleoprotein (RNP) catalytic core and additional proteins that modulate the ability of the RNP catalytic core to e...

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Autori principali: Hong, Kyungah, Upton, Heather, Miracco, Edward J., Jiang, Jiansen, Zhou, Z. Hong, Feigon, Juli, Collins, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811867/
https://ncbi.nlm.nih.gov/pubmed/23918804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00792-13
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