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Leptospiral LruA Is Required for Virulence and Modulates an Interaction with Mammalian Apolipoprotein AI

Leptospirosis is a worldwide zoonosis caused by spirochetes of the genus Leptospira. While understanding of pathogenesis remains limited, the development of mutagenesis in Leptospira has provided a powerful tool for identifying novel virulence factors. LruA is a lipoprotein that has been implicated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Kunkun, Murray, Gerald L., Seemann, Torsten, Srikram, Amporn, Bartpho, Thanatchaporn, Sermswan, Rasana W., Adler, Ben, Hoke, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811782/
https://ncbi.nlm.nih.gov/pubmed/23918777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01195-12
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