Cross-protective Immunity Against Leptospirosis Elicited by a Live, Attenuated Lipopolysaccharide Mutant

Background. Leptospira species cause leptospirosis, a zoonotic disease found worldwide. Current vaccines against leptospirosis provide protection only against closely related serovars. Methods. We evaluated an attenuated transposon mutant of Leptospira interrogans serovar Manilae (M1352, defective i...

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Detalhes bibliográficos
Main Authors: Srikram, Amporn, Zhang, Kunkun, Bartpho, Thanatchaporn, Lo, Miranda, Hoke, David E., Sermswan, Rasana W., Adler, Ben, Murray, Gerald L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071135/
https://ncbi.nlm.nih.gov/pubmed/21220775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq127
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