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Streptomyces coelicolor Polynucleotide Phosphorylase Can Polymerize Nucleoside Diphosphates under Phosphorolysis Conditions, with Implications for the Degradation of Structured RNAs
We have examined the ability of wild-type polynucleotide phosphorylase (PNPase) from Streptomyces coelicolor and two mutant forms of the enzyme, N459D and C468A, to function in the polymerization of ADP and in the phosphorolysis of RNA substrates derived from the S. coelicolor rpsO-pnp operon. The w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811585/ https://ncbi.nlm.nih.gov/pubmed/24039261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00936-13 |
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