Engineered Biosynthesis of Disaccharide-Modified Polyene Macrolides

Recent work has uncovered genes for two glycosyltransferases that are thought to catalyze mannosylation of mycosaminyl sugars of polyene macrolides. These two genes are nypY from Pseudonocardia sp. strain P1 and pegA from Actinoplanes caeruleus. Here we analyze these genes by heterologous expression...

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Detaylı Bibliyografya
Asıl Yazarlar: De Poire, Eimear, Stephens, Niamh, Rawlings, Bernard, Caffrey, Patrick
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Biotechnology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811359/
https://ncbi.nlm.nih.gov/pubmed/23913424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02197-13
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