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Engineered Biosynthesis of Disaccharide-Modified Polyene Macrolides

Recent work has uncovered genes for two glycosyltransferases that are thought to catalyze mannosylation of mycosaminyl sugars of polyene macrolides. These two genes are nypY from Pseudonocardia sp. strain P1 and pegA from Actinoplanes caeruleus. Here we analyze these genes by heterologous expression...

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Detalhes bibliográficos
Main Authors: De Poire, Eimear, Stephens, Niamh, Rawlings, Bernard, Caffrey, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811359/
https://ncbi.nlm.nih.gov/pubmed/23913424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02197-13
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