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Impact of In Vivo Triazole and Echinocandin Combination Therapy for Invasive Pulmonary Aspergillosis: Enhanced Efficacy against Cyp51 Mutant Isolates

Previous studies examining combination therapy for invasive pulmonary aspergillosis (IPA) have revealed conflicting results, including antagonism, indifference, and enhanced effects. The most commonly employed combination for this infection includes a mold-active triazole and echinocandin. Few studi...

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Autors principals: Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Andes, David R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811282/
https://ncbi.nlm.nih.gov/pubmed/23959322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00833-13
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